For the last decade, interdisciplinary science research has been blossoming in developing countries. However, the development does not coincide with the natural demand of how the research should be conducted in which intense innovative approaches and effective networking across disciplines is required. The slow progress of interdisciplinary science education in most part of developing countries cannot apart from the fact that education practices are still based on teacher-centred conventional paradigm. The traditional approach which is widely practiced until now inhibits students to develop innovative thinking and inquiry skills which are the basic requirements for their capacity development in producing scientific reasoning. Moreover, many educators in higher education institutions are not aware or do not have sufficient skills to observe and to overcome the impact of the traditional approach to the university students. The other inhibitor arises from the limited network and exposure of the researchers and students in the developing countries to international research. International exposure can act as a catalyst to inspire students and researchers to shift their paradigm towards learner-centred education. On the other side, many researchers in developing countries still hold the view that high quality research should bear high cost. A principle which is also adopted widely by higher education authorities in their policies. The EduLab-Net Wiser project is aimed to stimulate the paradigm shifting in doing interdisciplinary science research and education in developing countries based on the principle of innovation and international network as a catalyst. Web-based interaction will be employed to optimize the transfer of learning by taking into account the socio-economical context in the developing countries.